Demographic characteristics, thromboembolism risk, and treatment patterns for patients with cold agglutinin disease in Japan
| Autor: | Toyomi Kamesaki, Jaime Morales, Hideho Wada, Elisa Tsao, Junichi Nishimura, Yuzuru Kanakura, Eric Yu |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Risk medicine.medical_specialty Cold agglutinin disease Myocardial Infarction Datasets as Topic CAD Disease Veins Cohort Studies 03 medical and health sciences 0302 clinical medicine Japan Internal medicine Thromboembolism Medicine Humans cardiovascular diseases Aged Retrospective Studies Aged 80 and over business.industry Incidence (epidemiology) Incidence Hematology Odds ratio Arteries Middle Aged medicine.disease Confidence interval 030220 oncology & carcinogenesis Cohort Female Anemia Hemolytic Autoimmune Autoimmune hemolytic anemia business 030215 immunology |
| Zdroj: | International journal of hematology. 112(3) |
| ISSN: | 1865-3774 |
| Popis: | Cold agglutinin disease (CAD) is a rare, complement-mediated autoimmune hemolytic anemia. Patients with CAD in the United States and Europe have an increased incidence of thromboembolism (TE), but comparable information for patients in other regions is lacking. Thus, we examined TE risk for patients with CAD in Japan. Patients with CAD (at least three claims with a CAD diagnosis; Japanese Disease Code 2830009) and non-CAD controls were retrospectively identified (2008–2017) from a large hospital-based administrative claims dataset in Japan. Cohorts were compared using conditional logistic regression. We identified 344 patients with CAD (53.2% female; mean age: 66.8 years) and 3440 matched controls. Patients with CAD had higher TE rates than controls (34.9% vs. 17.9%; P |
| Databáze: | OpenAIRE |
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