High serum hepatocyte growth factor levels in the acute stage of community-acquired infectious diseases

Autor: Aril Frydén, Ingela Nilsson, Lars Brudin, Pia Forsberg, Fariba Nayeri, Claes Söderström
Rok vydání: 2002
Předmět:
Zdroj: Scandinavian journal of infectious diseases. 34(2)
ISSN: 0036-5548
Popis: Acute serum levels of hepatocyte growth factor (HGF) were studied in 6 clinical groups with (i) gastroenteritis, (ii) skin and soft tissue infection, (iii) urinary tract infection, (iv) septicemia, (v) influenza, and (vi) chronic hepatitis C in comparison with a normal control group using an enzyme-linked immunosorbent assay method. We found that serum HGF levels were significantly higher in patients with acute infectious diseases (p < 0.0001) compared to patients with chronic viral hepatitis and healthy controls. Serum HGF and CRP levels were correlated significantly (r = 0.65, p < 10-7). We conclude that serum HGF levels are elevated in patients with acute infectious diseases.
Databáze: OpenAIRE