Metabolic Profile and Body Composition in Twins Concordant and Discordant for Physical Exercise
| Autor: | Michelle Vasconcelos de Oliveira Borges, Telma Maria Araújo Moura Lemos, Elys Costa de Sousa, José Ronaldo Ribeiro da Costa, Jeane Franco Pires Medeiros, Paulo Moreira Silva Dantas |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Blood Glucose Male Concordance Physiology 030209 endocrinology & metabolism Physical exercise 03 medical and health sciences Young Adult 0302 clinical medicine Medicine Humans Exercise Genetics (clinical) medicine.diagnostic_test business.industry Causal effect Obstetrics and Gynecology VO2 max Cardiorespiratory fitness 030229 sport sciences Twins Monozygotic Lipids Pediatrics Perinatology and Child Health Body Composition Metabolome Female business Lipid profile Ventilatory threshold Metabolic profile Brazil |
| Zdroj: | Twin research and human genetics : the official journal of the International Society for Twin Studies. 23(4) |
| ISSN: | 1832-4274 |
| Popis: | The aim of this study was to evaluate the differences in the metabolic profile and body composition of monozygotic (MZ) twins concordant and discordant for the practice of physical exercise. The sample consisted of 92 MZ twins (72.5% female and 27.5% male, mean age 25.4 ± 5.69 years), registered with the Brazilian Registry of Twins, residing in Natal, Brazil. Data collection was carried out between the years 2016 and 2018. On day 1, subjects underwent a whole-body fitness evaluation, including measures of weight, height, body composition by Dual-Energy X-ray Absorptiometry and the Cardiorespiratory Exercise Test. On day 2, 10 ml blood samples were collected (overnight fasting) to determine the lipid profile and fasting glucose. The sample was separated into three groups: Active Concordant twins (Concordant A, n = 44 subjects), Inactive Concordant twins (Concordant I, n = 22 subjects) and Discordant pairs for Physical Exercise (Discordant PE, n = 26 subjects). The results demonstrated a difference between the discordant twins for exercise and also between the active versus sedentary groups, indicating a causal effect of exercise on the fat percentage, maximum oxygen consumption (VO2max) and second ventilatory threshold variables. Between groups, a difference was also observed between the groups in ventilatory threshold, very low-density lipoprotein and triglycerides. We concluded that, regardless of genetics, the practice of physical exercise was sufficient to generate alterations in body composition and VO2max in MZ twins, but not in the lipid profile or fasting glucose. |
| Databáze: | OpenAIRE |
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