Relation between red blood cell distribution width and acute kidney injury in patients with sepsis
Autor: | Marina Larissa Vettorello Ramires, Manoela Fidelis Batista Leite, Daniel Zu Yow Lo, Leonardo Bonilla da Silveira, Leonardo José Rolim Ferraz, Andreia Pardini, Araci Massami Sakashita, Andrea Tiemi Kondo, Guilherme Benfatti Olivato, Marcelino de Souza Durão, Adelson Marçal Rodrigues, Daniela Mendes Chiloff, Danilo Candido de Almeida, Miguel Angelo Goes |
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Rok vydání: | 2021 |
Předmět: | |
Zdroj: | einstein (São Paulo) v.20 2022 Einstein (São Paulo) Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) instacron:IIEPAE |
ISSN: | 2317-6385 |
Popis: | Objective The objective of the present study is to evaluate the association of red blood cell distribution width with acute kidney injury in sepsis. Methods This is a retrospective study of 849 critically ill patients with sepsis in intensive care unit. Demographic data, renal function, inflammation, complete blood count, and acid-base parameters were compared between acute kidney injury and non-acute kidney injury groups. Therefore, a multivariate analysis was performed to observe independent predictive factors. Results Comparatively, higher levels of C-reactive protein, lactate, red blood cell distribution width, and Simplified Acute Physiology Score 3 were found in the acute kidney injury group. The study showed a higher frequency of women, hemoglobin (Hgb) concentration, platelets, bicarbonate and PaO2/FiO2 ratio in the non-acute kidney injury group. In addition, there was an independent association of comorbidity-chronic kidney disease [OR 3.549, 95%CI: 1.627-7.743; p |
Databáze: | OpenAIRE |
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