Factors associated with disability in patients with ulcerative colitis: A cross-sectional study

Autor: Renata D'Incà, Carla Marinelli, Edoardo Savarino, R. Caccaro, Greta Lorenzon, A. Rigo, Fabiana Zingone, M. Inferrera, Sonia Facchin
Rok vydání: 2019
Předmět:
Zdroj: Journal of digestive diseasesREFERENCES. 21(2)
ISSN: 1751-2980
Popis: OBJECTIVES Ulcerative colitis (UC) can give rise to several restrictions of patients' working and social activities. We aimed to determine the association between disease chronicity and the state of disability in a large population with UC. METHODS We recruited consecutive patients with UC attending the inflammatory bowel disease (IBD) unit of the Azienda Ospedaliera of Padua between July and December 2017. We collected patients' characteristics and clinical information, and all participants completed the IBD questionnaire (IBDQ) for quality of life assessment and the IBD disability index (IBD-DI) questionnaire. Using univariate logistic regression models we assessed whether the patients' characteristics and IBD-related variables were associated with an IBD-DI score ≤3.5. Statistically significant variables in the univariate analyses were then included in a multivariate regression model. Correlations between IBD-DI and all the above mentioned characteristics were investigated using the Spearman's rank correlation coefficient. RESULTS We included 201 patients. A positive correlation was observed between IBD-DI and IBDQ (r = 0.82, P
Databáze: OpenAIRE