Leptin as a marker of sexual dimorphism in newborn infants
| Autor: | Inês Maria Crespo Gutierres Pardo, Bruno Geloneze, Marcos Antonio Tambascia, José L. Pereira, Antonio de Azevedo Barros Filho |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Leptin
Male medicine.medical_specialty Birth weight Population Physiology Gestational Age Umbilical cord Sex Factors Internal medicine medicine Birth Weight Humans Testosterone education Sex Characteristics education.field_of_study Pregnancy Fetus Estradiol business.industry Infant Newborn Gestational age Fetal Blood medicine.disease Body Height Sexual dimorphism Cross-Sectional Studies medicine.anatomical_structure Endocrinology Pediatrics Perinatology and Child Health Female business Biomarkers |
| Zdroj: | Jornal de Pediatria. 80:305-308 |
| ISSN: | 0021-7557 |
| DOI: | 10.2223/1204 |
| Popis: | Objective: To determine cord blood leptin levels in newborns appropriate for gestational age, according to gender, birth weight, birth height and ponderal index. Methods: A cross-sectional study was carried out with 132 term newborns appropriate for gestational age (68 females, 64 males), gestational age between 35-42 weeks. Data were collected through interviews with the mothers at the maternity, anthropometrycal study of the newborns, and cord blood estradiol, testosterone and leptin assays obtained immediately after birth. Results: The levels of leptin were significantly higher in females than in males (8.34‐0.65 ng/ml versus 6.06‐0.71 ng/ml; p = 0.000). The concentrations of estradiol and testosterone did not differ between males and females. Leptin levels were positively correlated with gestational age (r = 0.394, p < 0.01), birth weight (r = 0.466, p < 0.01), birth length (r†= 0.335, p < 0.01) and ponderal index (r = 0.326, p† |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|