Cassava starch fermentation wastewater: characterization and preliminary toxicological studies
| Autor: | Edna Regina Amante, R. Tramonte, Gerson Luis Faccin, Rossana Podestá, N.M.A. de Souza, Manoela Alano Vieira, Sandra Regina Paulon Avancini, Angela Angeloni Rovaris |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Manihot Starch Toxicology Waste Disposal Fluid Drug Administration Schedule law.invention Probiotic chemistry.chemical_compound Residue (chemistry) Mice law Lactobacillus Animals Food science Rats Wistar biology Dose-Response Relationship Drug food and beverages General Medicine biology.organism_classification Lactic acid Rats Biochemistry Wastewater chemistry Toxicity Fermentation Female Food Science |
| Zdroj: | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 45(11) |
| ISSN: | 0278-6915 |
| Popis: | Cassava starch fermentation wastewater is an industrial residue composed mainly of lactic acid bacteria with predominance of the genera Lactobacillus, and organic acids. To evaluate the safety of this residue for possible production of probiotic beverages, acute in mice and sub-chronic (28-day repeated dose) toxicity studies in rats were carried. The administration of a single dose of 5 g/kg/body weight did not produce mortality in mice. Rats treated with water containing 0 (control), 25%, 50%, and 100% of the residue for 28 days, did not present alterations in behaviour or in food and water consumption. There were no treatment-related changes of toxicological significance in the relative weight of the organs neither in the haematological nor in the biochemical parameters. Histopathologic alterations observed in the small intestine did not seem to be associated with the treatment. |
| Databáze: | OpenAIRE |
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