Onset of adult-onset Still’s disease following influenza vaccination
| Autor: | Katsunobu Yoshioka, Mieko Minami, Tetsuya Aoki, Hiroko Oba, Shunsuke Fujimoto |
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| Rok vydání: | 2011 |
| Předmět: |
Fever
Influenza vaccine Prednisolone medicine.disease_cause Methylprednisolone Influenza A Virus H1N1 Subtype Rheumatology medicine Sore throat Influenza A virus Humans Glucocorticoids business.industry Vaccination Pharyngitis Exanthema Middle Aged Arthralgia Rash Influenza Vaccines Immunology Female medicine.symptom business Still's Disease Adult-Onset medicine.drug |
| Zdroj: | Modern Rheumatology. 21:432-435 |
| ISSN: | 1439-7609 1439-7595 |
| DOI: | 10.1007/s10165-011-0418-7 |
| Popis: | We describe that case of a 61-year-old woman who developed high spiking fever, sore throat, polyarthralgia, and salmon pink evanescent rash following influenza vaccination. A diagnosis of adult-onset Still's disease (AOSD) was made based on clinical and laboratory findings. Methylprednisolone pulse therapy followed by oral prednisolone resulted in a favorable outcome. This is the second published case in which a causal relationship between vaccination and onset of AOSD is suggested. Bystander activation would appear to play an important role in inducing the immune reaction. |
| Databáze: | OpenAIRE |
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