Small molecule induced control in duplex and triplex DNA-directed chemical reactions
Autor: | Jens B. Ravnsbæk, Kurt V. Gothelf, Mikkel F. Jacobsen |
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Rok vydání: | 2010 |
Předmět: |
Azides
Binding Sites Base Sequence Chemistry Berberine Alkaloids Organic Chemistry Triplex DNA DNA Biochemistry Chemical reaction Small molecule Combinatorial chemistry Catalysis chemistry.chemical_compound Duplex (building) Alkynes Quinolines Nucleic Acid Conformation Organic chemistry Physical and Theoretical Chemistry Copper |
Zdroj: | Org. Biomol. Chem.. 8:50-52 |
ISSN: | 1477-0539 1477-0520 |
DOI: | 10.1039/b919387a |
Popis: | Triplex DNA binders can effectively control copper-catalysed alkyne-azide click reactions in DNA architecture, such that either duplex or triplex DNA directed reactions of terminally attached azides and alkynes occur, in the absence or presence of triplex DNA binder, respectively. |
Databáze: | OpenAIRE |
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