A Review on the Foodomics Based on Liquid Chromatography Mass Spectrometry

Autor:	Yoshio, Muguruma, Mari, Nunome, Koichi, Inoue
Rok vydání:	2022
Předmět:	Drug Discovery Humans Metabolomics General Chemistry General Medicine Food Analysis Mass Spectrometry Chromatography Liquid
Zdroj:	Chemical and Pharmaceutical Bulletin. 70:12-18
ISSN:	1347-5223 0009-2363
DOI:	10.1248/cpb.c21-00765
Popis:	Due to the globalization of food production and distribution, the food chain has become increasingly complex, making it more difficult to evaluate unexpected food changes. Therefore, establishing sensitive, robust, and cost-effective analytical platforms to efficiently extract and analyze the food-chemicals in complex food matrices is essential, however, challenging. LC/MS-based metabolomics is the key to obtain a broad overview of human metabolism and understand novel food science. Various metabolomics approaches (e.g., targeted and/or untargeted) and sample preparation techniques in food analysis have their own advantages and limitations. Selecting an analytical platform that matches the characteristics of the analytes is important for food analysis. This review highlighted the recent trends and applications of metabolomics based on "foodomics" by LC-MS and provides the perspectives and insights into the methodology and various sample preparation techniques in food analysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ab84ddf554b40f5981f890e3597029 https://doi.org/10.1248/cpb.c21-00765 Zobrazit plný text záznamu