Is combined cataract surgery associated with acute postoperative endophthalmitis? A nationwide study from 2005 to 2014

Autor: Vincent Daien, Jean-François Korobelnik, Eric Benzenine, Alain M. Bron, Catherine Quantin, Anne Sophie Mariet, Catherine Creuzot-Garcher
Přispěvatelé: Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), Service Biostatistiques et Informatique Médicale (CHU de Dijon) (DIM), Centre d'Investigation Clinique 1432 (Dijon) - Module Plurithématique : Périnatalité Cancérologie Handicap et Ophtalmologie (CIC-P803), Université de Bourgogne (UB)-Direction Générale de l'Organisation des Soins (DGOS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre d'Investigation Clinique 1432 (Dijon) - Epidemiologie Clinique/Essais Cliniques (CIC-EC), Université de Bourgogne (UB)-Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon)-Institut National de la Santé et de la Recherche Médicale (INSERM), Biostatistique, Biomathématique, Pharmacoépidémiologie et Maladies Infectieuses (B2PHI), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut Pasteur [Paris] (IP)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Biotechnologie et Microbiologie Appliquée (LBMA), Université Bordeaux Segalen - Bordeaux 2-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Neuropsychiatrie : recherche épidémiologique et clinique (PSNREC), Université Montpellier 1 (UM1)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), CHU Bordeaux [Bordeaux], Institut National de la Santé et de la Recherche Médicale (INSERM)-Direction Générale de l'Organisation des Soins (DGOS)-Université de Bourgogne (UB), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut Pasteur [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Montpellier 1 (UM1)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)
Jazyk: angličtina
Rok vydání: 2019
Předmět:
genetic structures
Epidemiology
medicine.medical_treatment
MESH: Registries
Glaucoma
MESH: Postoperative Complications/epidemiology
Rate ratio
Eye Infections
Bacterial

Postoperative Complications
0302 clinical medicine
MESH: Cataract Extraction/adverse effects
Risk Factors
MESH: Risk Factors
Medicine
Registries
030212 general & internal medicine
MESH: Incidence
MESH: Surgical Wound Infection/epidemiology
Endophthalmitis
MESH: France/epidemiology
Incidence
Incidence (epidemiology)
Sensory Systems
Acute Disease
MESH: Acute Disease
France
Infection
Cohort study
medicine.medical_specialty
Cataract Extraction
03 medical and health sciences
Cellular and Molecular Neuroscience
MESH: Phacoemulsification/adverse effects
MESH: Endophthalmitis/epidemiology
Humans
Surgical Wound Infection
Retrospective Studies
Phacoemulsification
MESH: Humans
business.industry
MESH: Eye Infections
Bacterial/epidemiology

MESH: Retrospective Studies
Cataract surgery
medicine.disease
eye diseases
Surgery
Ophthalmology
030221 ophthalmology & optometry
sense organs
business
Acute postoperative endophthalmitis
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Zdroj: British Journal of Ophthalmology
British Journal of Ophthalmology, 2019, 103 (4), pp.534-538. ⟨10.1136/bjophthalmol-2018-312171⟩
British Journal of Ophthalmology, BMJ Publishing Group, 2019, 103 (4), pp.534-538. ⟨10.1136/bjophthalmol-2018-312171⟩
ISSN: 0007-1161
1468-2079
DOI: 10.1136/bjophthalmol-2018-312171⟩
Popis: PurposeTo assess the incidence of acute postoperative endophthalmitis (POE) after cataract surgery combined with corneal, glaucoma or vitreoretinal surgical procedures from 2005 to 2014 in France.MethodsIn this cohort study, acute POE occurring within 6 weeks after surgery was identified by means of billing codes recorded in a national database in patients operated for cataract extraction with phacoemulsification, or corneal, glaucoma or vitreoretinal surgical procedures, either combined or stand-alone.ResultsFrom January 2005 to December 2014, up to 6 260 477 eyes underwent phacoemulsification cataract surgery as a single procedure and 115 468 eyes underwent phacoemulsification combined with corneal, glaucoma or vitreoretinal surgical procedures. The crude incidence of acute POE after stand-alone or combined cataract surgery was 0.102% and 0.149%, respectively. In multivariate Poisson analysis, combined surgery taken as a whole was at higher risk than cataract stand-alone surgery, with an adjusted incidence rate ratio (IRR) (95% CI) of 1.38 (1.11 to 1.70; p=0.0054). Glaucoma surgeries were associated with a lower acute POE incidence compared with phacoemulsification, conversely to vitreoretinal surgical procedures: IRR 0.63 (0.47 to 0.85; pConclusionA higher incidence of acute POE after combined cataract surgery than after cataract surgery done as a stand-alone procedure was observed based on the French nationwide medical-administrative database. The incidence of acute POE after combined surgery was related to the type of surgery performed simultaneously with cataract extraction.
Databáze: OpenAIRE