Outcome for bilateral cochlear implantation in patients with congenital Cytomegalovirus infection
| Autor: | I. Rouillon, M. Blanchard, Vincent Couloigner, M. Parodi, Françoise Denoyelle, I. Prang, C. Courtois, A. De Lamaze, Natalie Loundon |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Congenital cytomegalovirus infection Deafness Medium term Congenital cmv infection 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Humans In patient Child 030223 otorhinolaryngology Cochlear implantation Retrospective Studies business.industry Retrospective cohort study medicine.disease Cochlear Implantation Magnetic Resonance Imaging Cochlear Implants Treatment Outcome Otorhinolaryngology 030220 oncology & carcinogenesis Cytomegalovirus Infections Speech Perception Surgery business |
| Zdroj: | European Annals of Otorhinolaryngology, Head and Neck Diseases. 138:337-341 |
| ISSN: | 1879-7296 |
| DOI: | 10.1016/j.anorl.2021.01.002 |
| Popis: | Objectives To analyze the impact of bilateral cochlear implantation (CI) on perceptual and linguistic development in hearing-impaired children with congenital Cytomegalovirus (CMV) infection. Patients and method A retrospective study was performed for the period 1991-2016 in a pediatric CI reference center. Closed Set Word (CSW) recognition scores, Categories of Auditory Performance (CAP) and linguistic level on the MT Lenormand scale (MTL) were compared between bilateral (Bi) and unilateral (Uni) groups 12, 24 and 36 months after first CI (CI-1). Results 84 patients with congenital CMV infection who underwent CI were included, in 2 groups: sequential or simultaneous bilateral CI (Bi) (N = 20), and unilateral CI (Uni) (N = 64). Twelve, 24 and 36 months after CI-1, CSW scores were 35.56%, 64.52% and 82.93% in Uni and 60.3%, 85% (P = 0.0084*), and 100% (P = 0.00085*) in Bi. CAP scores 12, 24 and 36 months after CI-1 were 2.57, 3.85 and 4.3 in Uni and 3.91 (P = 0.0068*), 5.00 (p = 0.029*) and 5.50 (P = 0.051*) in Bi. MTL linguistic level scores at 12, 24 and 36 months were 0.72, 1.25 and 1.65 in Uni, and 1.72, 3 (P = 0.033) and 3.11 (P = 0.045) in Bi. These significantly better scores in Bi at 24 and 36 months after CI-1 were also found on analysis of subgroups with no associated neurologic disorder (P = 0.046* and P = 0.032*), no associated psychiatric pathology (P = 0.0055* and P = 0.0073*), and no other associated disorder (P = 0.0018* and P = 0.035*), and for all subgroups together (P = 0.0036 and P = 0.037). Conclusion Bilateral CI is a faster way than unilateral CI for patients with congenital CMV infection to achieve structured fluent oral language. 50% of the series showed cerebral abnormalities on MRI, without difference between groups. This was not in itself predictive of poor progression of oral communication, unless associated with major neurologic disorder. Some children made little or no use of their CI in the medium term. |
| Databáze: | OpenAIRE |
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