Markedly elevated lipase as the first manifestation of celiac disease: Case Report
Autor: | Fazıl Hunutlu, Macit Gülten, Nesrin Uğraş, Ahmet Z. Sahin |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
General and Internal Medicine Hyperlipasemia business.industry celiac disease hyperlipasemia macrolipasemia pancreatic hyperenzymemia Disease Gastroenterology Elevated Lipase Internal medicine medicine General Earth and Planetary Sciences business Genel ve Dahili Tıp General Environmental Science |
Zdroj: | Volume: 3, Issue: 2 80-84 Turkish Journal of Internal Medicine |
ISSN: | 2687-4245 |
Popis: | Lipase is a hydrolytic enzyme and commonly used for the diagnosis of pancreatitis with amylase. Except for pancreatitis, lipase is elevated in many clinical conditions such as hepatobiliary disorders, bowel diseases, malignancies, renal impairment. Celiac disease (CD) should be considered as one of the causes. In patients with CD, the frequency of pancreatic hyperenzymemia and possible pathophysiological mechanisms are not well studied. To date, several mechanisms explaining pancreatic hyperenzymemia in CD are reported. Malnutrition, disease bowel induced pancreatic dysfunction, autoimmune pancreatic inflammation, and macroenzymemia are the main ones. Herein, we report a patient with newly diagnosed CD, representing markedly elevated serum lipase level with normal amylase. |
Databáze: | OpenAIRE |
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