Reduced mildly oxidized LDL in young female athletes
| Autor: | Marjo Lehtonen-Veromaa, Jorma Viikari, Markku Ahotupa, Olli J. Heinonen, Tommi Vasankari, Aila Leino, Timo Möttönen, Kerttu Irjala |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
Adolescent Physical activity Physical exercise Body Mass Index chemistry.chemical_compound Reference Values Internal medicine Humans Medicine Child Ldl cholesterol biology Athletes Cholesterol business.industry Cholesterol HDL Cholesterol LDL biology.organism_classification Lipoproteins LDL Endocrinology chemistry Basal metabolic rate Female lipids (amino acids peptides and proteins) Cardiology and Cardiovascular Medicine business human activities Body mass index Oxidized ldl Sports |
| Zdroj: | Atherosclerosis. 151:399-405 |
| ISSN: | 0021-9150 |
| DOI: | 10.1016/s0021-9150(99)00401-3 |
| Popis: | We investigated the effect of physical activity and sports participation on LDL oxidation in vivo and on lipid risk factors in 183 teenage girls (9-15 years): 64 gymnasts, 61 runners, and 58 controls. Oxidized LDL was measured as baseline levels of conjugated dienes in LDL lipids (ox-LDL). The gymnasts had a 15% lower ratio of LDL conjugated dienes to LDL cholesterol (ox-LDL:LDL ratio, P = 0.0052) compared to controls, and the difference persisted when the body mass index was included as a covariate (ANCOVA, P = 0.013). Also, the gymnasts had a 12% higher ratio of HDL cholesterol to total cholesterol than the controls (ANCOVA, P = 0.046). There were no differences in the other common lipid risk factors between the groups. The ox-LDL:LDL ratio correlated negatively with HDL cholesterol (r = -0.23, P=0.0021) and with physical activity METs (multiples of resting metabolic rate) (r = -0.21, P=0.0040). Our study strengthens the evidence that the atherogenic risk is influenced favourably by physical exercise and sporting activities as early as in adolescents. This risk reduction is associated with lower mildly oxidized LDL in adolescent girls. |
| Databáze: | OpenAIRE |
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