A possible genetic component of obesity in childhood. Observations on acid phosphatase polymorphism
| Autor: | M. Macioce, P. Borgiani, Egidio Bottini, N. Lucarini, G. Finocchi, A. Amante, Fulvia Gloria-Bottini |
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| Rok vydání: | 1990 |
| Předmět: |
Male
Erythrocytes Adolescent Phosphatase Acid Phosphatase Cellular and Molecular Neuroscience medicine Humans Genetic variability Obesity Child Molecular Biology Pharmacology Differential modulation chemistry.chemical_classification Polymorphism Genetic biology Genetics of obesity Acid phosphatase Cell Biology medicine.disease Phenotype Enzyme Biochemistry chemistry Child Preschool biology.protein Molecular Medicine Female |
| Zdroj: | Experientia. 46(1) |
| ISSN: | 0014-4754 |
| Popis: | Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association. |
| Databáze: | OpenAIRE |
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