Clinical Validity of the Mattis Dementia Rating Scale-2 in Parkinson Disease With MCI and Dementia
| Autor: | Evelyne Matteau, Nicolas Dupré, Martine Simard, Pierre Provencher, Mélanie Langlois |
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| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Cross-sectional study Perseveration Disease Dementia rating scale Neuropsychological Tests Audiology Standard score Sensitivity and Specificity behavioral disciplines and activities Memory mental disorders medicine Humans Dementia Attention Cognitive Dysfunction Medical diagnosis Psychiatry Aged Aged 80 and over Psychiatric Status Rating Scales Reproducibility of Results Parkinson Disease Middle Aged medicine.disease nervous system diseases Psychiatry and Mental health Cross-Sectional Studies Ceiling effect Female Neurology (clinical) Geriatrics and Gerontology medicine.symptom Psychology |
| Zdroj: | Journal of Geriatric Psychiatry and Neurology. 25:100-106 |
| ISSN: | 1552-5708 0891-9887 |
| Popis: | The utility of the Mattis Dementia Rating Scale 2 (MDRS-2) in screening for dementia in Parkinson disease (PD) is well documented. However, little is known about its sensitivity to mild cognitive impairment in PD (PD-MCI). This study sought to document the validity of the MDRS-2 for diagnoses of PD-MCI and dementia in PD (PDD). Twenty-two healthy controls (HCs), 22 PD-MCI, and 16 PDD were compared on each MDRS-2 subscales and MDRS-2 total standard scores. Patients with PDD performed significantly worse than the other groups (all Ps < .05) on the MDRS-2 total and on all subscales, except attention. PD-MCI had significant lower scores than HCs on the MDRS-2 total and on initiation/perseveration and memory subscales. The optimal cutoff score for PD-MCI diagnosis was ≤ 140/144 and ≤ 132/144 for PDD. These findings suggest that MDRS-2 is a useful tool to identify dementia but that there might be a ceiling effect in the MDRS-2 cutoff score to diagnose MCI in PD. |
| Databáze: | OpenAIRE |
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