Recent Expansion of a New Ingi-Related Clade of Vingi non-LTR Retrotransposons in Hedgehogs
| Autor: | Vladimir V. Kapitonov, Kenji K. Kojima, Jerzy Jurka |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Retroelements
Molecular Sequence Data Retrotransposon Genome Evolution Molecular Vertical transfer Phylogenetics Genetics Animals Humans Letters Clade RNase H Molecular Biology Hedgehog Phylogeny Ecology Evolution Behavior and Systematics Base Sequence biology Terminal Repeat Sequences food and beverages Hedgehogs Horizontal gene transfer biology.protein |
| Zdroj: | Molecular Biology and Evolution. 28:17-20 |
| ISSN: | 1537-1719 0737-4038 |
| DOI: | 10.1093/molbev/msq220 |
| Popis: | Autonomous non-long terminal repeat (non-LTR) retrotransposons and their repetitive remnants are ubiquitous components of mammalian genomes. Recently, we identified non-LTR retrotransposon families, Ingi-1_AAl and Ingi-1_EE, in two hedgehog genomes. Here we rename them to Vingi-1_AAl and Vingi-1_EE and report a new clade ‘‘Vingi,’’ which is a sister clade of Ingi that lacks the ribonuclease H domain. In the European hedgehog genome, there are 11 nonautonomous families of elements derived from Vingi-1_EE by internal deletions. No retrotransposons related to Vingi elements were found in any of the remaining 33 mammalian genomes nearly completely sequenced to date, but we identified several new families of Vingi and Ingi retrotransposons outside mammals. Our data suggest the horizontal transfer of Vingi elements to hedgehog, although the vertical transfer cannot be ruled out. The compact structure and trans-mobilization of nonautonomous derivatives of Vingi can make them useful for in vivo retrotransposition assay system. |
| Databáze: | OpenAIRE |
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