Long-term quality of life in octogenarians and nonagenarians with nonvalvular atrial fibrillation following WATCHMAN™ device implantation
| Autor: | Abdulah Alrifai, Elie Donath, Robert Chait, Jesus Pino, Fergie Ramos Tuarez, Julio Grajeda Chavez, Marcelo Jimenez, Jorge Saona, Ximena Torres Diaz, Mohamad Kabach |
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| Rok vydání: | 2018 |
| Předmět: |
Male
medicine.medical_specialty Cardiac Catheterization Time Factors 030204 cardiovascular system & hematology Pericardial effusion 03 medical and health sciences 0302 clinical medicine Primary outcome Risk Factors Internal medicine Atrial Fibrillation medicine Humans Radiology Nuclear Medicine and imaging Atrial Appendage 030212 general & internal medicine Prospective Studies Thrombus Retrospective Studies Aged 80 and over business.industry Acute kidney injury Age Factors Retrospective cohort study Atrial fibrillation General Medicine Equipment Design medicine.disease humanities Stroke Treatment Outcome Cohort Quality of Life Female Cardiology and Cardiovascular Medicine business Major bleeding |
| Zdroj: | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac AngiographyInterventions. 93(6) |
| ISSN: | 1522-726X |
| Popis: | OBJECTIVES To assess the impact of WATCHMAN™ on quality of life (QoL) in octogenarians and nonagenarians. BACKGROUND QoL after WATCHMAN™ device in the elderly remains unknown. METHODS This is a prospective and retrospective cohort study of patients that underwent WATCHMAN™ implantation in a tertiary cardiovascular center from April 1, 2015 to September 27, 2017. The primary outcome was a prospective assessment of QoL via the SF-12v2 Health Survey (SF-12v2) in those aged ≥80 and ≥90 years. Secondary outcomes include major bleeding, stroke, vascular complications, pericardial effusion, device related thrombus (DRT), prolonged length of stay (LOS), acute kidney injury (AKI), and recurrent hospitalizations. RESULTS This cohort of 151 patients included 48/151 (32%) females with a mean age of 80 ± 7.7 years. Mean CHA2 DS2 -VASc was 4.38 ± 1.36 and mean HAS-BLED was 3.27 ± 1.17. Octogenarians 65/81(80%) and nonagenarians 16/81(20%) comprised 81/151(54%) of patients (mean age 86 ± 4.3 years) from which 36/65 (55%) octogenarians and 10/16 (63%) nonagenarians completed SF-12v2 evaluation at 22 ± 10 and 30 ± 10-months. Octogenarians demonstrated enhanced physical component scores (PCS), and nonagenarians equal PCS versus the age-adjusted norm (45.43 ± 9.84 versus 38.68 ± 11.04, P = 0.0003, and 41.26 ± 12.36 versus 38.68 ± 11.04, P = 0.6463, respectively). The mental component scores (MCS) of octogenarians and nonagenarians remained comparable (51.80 ± 9.56 and 48.97 ± 9.92 versus 50.06 ± 10.94, respectively, P = 0.4659). No stroke, vascular complications, pericardial effusions, or readmissions related to WATCHMAN™ occurred. No difference among patients |
| Databáze: | OpenAIRE |
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