Prophylactic nitric oxide treatment reduces incidence of bovine respiratory disease complex in beef cattle arriving at a feedlot
| Autor: | John S. Church, Gilly Regev-Shoshani, Allan L. Schaefer, Chris Miller, N.J. Cook |
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| Rok vydání: | 2013 |
| Předmět: |
Veterinary medicine
medicine.medical_specialty Time Factors Hematology General Veterinary Incidence (epidemiology) Bovine Respiratory Disease Complex Bovine respiratory disease Biology Beef cattle Nitric Oxide Placebo medicine.disease Housing Animal Animal science Stress Physiological Internal medicine Administration Inhalation Feedlot medicine Animals Cattle Adverse effect |
| Zdroj: | Research in Veterinary Science. 95:606-611 |
| ISSN: | 0034-5288 |
| DOI: | 10.1016/j.rvsc.2013.06.016 |
| Popis: | Bovine respiratory disease complex (BRDc), is a challenging multi-factorial health issue caused by viral/bacterial pathogens and stressors linked with the transport and mixing of cattle, negatively impacting the cattle feedlot industry. Nitric oxide (NO) is a naturally occurring molecule with antimicrobial attributes. This study tests whether NO can prevent the symptoms associated with BRDc. Eighty-five, crossbred, multiple-sourced, commingled commercial weaned beef calves were monitored and scored for temperature, white blood count, clinical score, hematology, cortisol levels and neutrophil/lymphocyte ratio. NO treatment or placebo were given once on arrival to the stockyard. After one week 87.5% of sick animals were from the control while 12.5% from treatment groups and after two weeks 72% and 28% respectively. Treatment was shown to be safe, causing neither distress nor adverse effects on the animals. These data show that NO treatment on arrival to the feedlot significantly decreased the incidence of BRDc in this study. |
| Databáze: | OpenAIRE |
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