Is clinical breast examination important for breast cancer detection?
| Autor: | Louise Provencher, Jean-Charles Hogue, Caroline Diorio, M. Joyal, Jocelyne Chiquette, Duchesne N, Éric Poirier, Christine Desbiens, Brigitte Poirier, Dominique K. Boudreau |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Oncology
medicine.medical_specialty mammography Physical examination Nipple discharge 03 medical and health sciences Breast cancer clinical examination 0302 clinical medicine Internal medicine medicine Mammography 030212 general & internal medicine skin and connective tissue diseases palpable breast masses medicine.diagnostic_test business.industry screening Cancer Retrospective cohort study ultrasonography Ductal carcinoma medicine.disease 030220 oncology & carcinogenesis Invasive lobular carcinoma Original Article Radiology medicine.symptom business |
| Zdroj: | Current Oncology Volume 23 Issue 4 Pages 2881-339 |
| Popis: | Screening clinical breast examination (cbe) is controversial the use of cbe is declining not only as a screening tool, but also as a diagnostic tool. In the present study, we aimed to assess the value of cbe in breast cancer detection in a tertiary care centre for breast diseases. This retrospective study of all breast cancers diagnosed between July 1999 and December 2010 at our centre categorized cases according to the mean of detection (cbe, mammography, or both). A cbe was considered &ldquo abnormal&rdquo in the presence of a mass, nipple discharge, skin or nipple retraction, edema, erythema, peau d&rsquo orange, or ulcers. During the study period, a complete dataset was available for 6333 treated primary breast cancers. Cancer types were ductal carcinoma in situ (15.3%), invasive ductal carcinoma (75.7%), invasive lobular carcinoma (9.0%), or others (2.2%). Of the 6333 cancers, 36.5% (n = 2312) were detected by mammography alone, 54.8% (n = 3470) by mammography and cbe, and 8.7% (n = 551) by physician-performed cbe alone (or 5.3% if considering ultrasonography). Invasive tumours diagnosed by cbe alone were more often triple-negative, her2-positive, node-positive, and larger than those diagnosed by mammography alone (p < 0.05). A significant number of cancers would have been missed if cbe had not been performed. Compared with cancers detected by mammography alone, those detected by cbe had more aggressive features. Clinical breast examination is a very low-cost test that could improve the detection of breast cancer and could prompt breast ultrasonography in the case of a negative mammogram. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|