CMR based measurement of aortic stiffness, epicardial fat, left ventricular myocardial strain and fibrosis in hypertensive patients
| Autor: | Rami Homsi, Alois M. Sprinkart, Michael Meier-Schroers, Christian Kropidlowski, Hans H. Schild, Daniel Kuetting, Daniel Thomas |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system Original Paper business.industry 030204 cardiovascular system & hematology medicine.disease Epicardial fat 03 medical and health sciences 0302 clinical medicine Fibrosis lcsh:RC666-701 Internal medicine Diabetes mellitus Myocardial strain medicine Cardiology Myocardial fibrosis Aortic stiffness 030212 general & internal medicine Cardiology and Cardiovascular Medicine business Cardiac magnetic resonance Pulse wave velocity |
| Zdroj: | International Journal of Cardiology. Heart & Vasculature International Journal of Cardiology: Heart & Vasculature, Vol 27, Iss, Pp-(2020) |
| ISSN: | 2352-9067 |
| Popis: | Introduction: A combined assessment of different parameters of cardiovascular (CV) risk and prognosis can be supportive and performed with cardiac magnetic resonance (CMR). Aortic stiffness, epicardial fat volume (EFV), left ventricular (LV) strain and fibrosis were evaluated within a single CMR examination and results were related to the presence of hypertension (HTN) and diabetes mellitus (DM). Methods: 20 healthy controls (57.2 ± 8.2 years(y); 26.2 ± 3.9 kg/m2), 31 hypertensive patients without DM (59.6 ± 6.7 y; 28.4 ± 4.7 kg/m2) and 12 hypertensive patients with DM (58.8 ± 9.9y; 30.7 ± 6.3 kg/m2) were examined at 1.5Tesla. Aortic stiffness was evaluated by calculation of aortic pulse wave velocity (PWV), EFV by a 3D-Dixon sequence. Longitudinal & circumferential systolic myocardial strain (LS; CS) were analyzed and T1-relaxation times (T1) were determined to detect myocardial fibrosis. Results: EFV was highest in hypertensive patients with diabetes (78.4 ± 28.0 ml/m2) followed by only hypertensive patients (64.2 ± 27.3 ml/m2) and lowest in controls (50.3 ± 22.7 ml/m2; p |
| Databáze: | OpenAIRE |
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