How I investigate Eosinophilia
| Autor: | Rebecca L. Larsen, Natasha M. Savage |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Clinical Biochemistry 030204 cardiovascular system & hematology Timely diagnosis World health 03 medical and health sciences 0302 clinical medicine Eosinophilic disorder Clinical history hemic and lymphatic diseases Eosinophilia Humans Medicine Hematopoietic Neoplasms Intensive care medicine business.industry Biochemistry (medical) Hematology General Medicine Guideline respiratory system Practice Guidelines as Topic Cellular Morphology medicine.symptom business 030215 immunology |
| Zdroj: | International Journal of Laboratory Hematology. 41:153-161 |
| ISSN: | 1751-553X 1751-5521 |
| DOI: | 10.1111/ijlh.12955 |
| Popis: | Eosinophilia is typically secondary, that is, reactive, in nature and is associated with a wide variety of neoplastic and non-neoplastic disorders. Clonal eosinophilia is also seen in a wide variety of hematopoietic neoplasms, and sub-classification can be diagnostically challenging. A proper evaluation of persistent eosinophilia involves correlation of clinical history, laboratory data, cellular morphology, and ancillary testing. Knowledge of appropriate ancillary testing is necessary for a timely diagnosis. We present a review of the literature regarding eosinophilia, including the 2016 World Health Organization (WHO) update of WHO-defined eosinophilic disorders. We also present a review of eosinophilia in a case-based format including guidelines for evaluation of both routine and challenging cases. The purpose of this guideline is not to provide an in-depth discussion of each diagnosis, but rather a practical method that all pathologists can utilize to investigate eosinophilia. |
| Databáze: | OpenAIRE |
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