Health-related Quality of Life of Breast Cancer Survivors Attending an Exercise Intervention Study: A Five-year Follow-up
Autor: | Hannu Kautiainen, Riku Nikander, Meri Utriainen, Tiina Saarto, Eija Roine, Riika Huovinen, Carl Blomqvist, Heidi Penttinen, Pirkko-Liisa Kellokumpu-Lehtinen, Leena Vehmanen, Harri Sintonen |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
Adult
Cancer Research medicine.medical_specialty Time Factors medicine.medical_treatment Population Breast Neoplasms General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Breast cancer Quality of life Cancer Survivors Internal medicine Surveys and Questionnaires Outcome Assessment Health Care Medicine Humans Prospective Studies education Depression (differential diagnoses) Aged Pharmacology education.field_of_study Rehabilitation Exercise intervention business.industry Cancer Middle Aged medicine.disease humanities 3. Good health Exercise Therapy Distress 030220 oncology & carcinogenesis Quality of Life Female business Research Article Follow-Up Studies |
Popis: | Background/Aim: As the number of breast cancer survivors is increasing, their long-term health-related quality of life (HRQoL) has become an important issue. The aim of the study is to follow up the HRQoL of breast cancer survivors (BCS) in a prospective randomized exercise intervention study and to compare HRQoL to that of the age-matched general female population. Patients and Methods: Following adjuvant treatment, 537 patients aged 35-68 and capable of exercise training were randomized to a 12-month exercise trial. In 182 of those patients, HRQoL was measured by the generic 15D at baseline and followed up for five years. Furthermore, the HRQoL of all BCS answering the 15D at five-year follow-up (n=390) was compared to that of a representative sample of the general population. Results: After five years, the BCS’ mean HRQoL demonstrated a statistically and clinically significant impairment compared to that of the general population (difference –0.023, p |
Databáze: | OpenAIRE |
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