Intraocular straylight before and after low myopic photorefractive keratectomy with and without mitomycin C

Autor: Marcelo V. Netto, Tais Renata Ribeiro Parede, Samir J. Bechara, Andre A.M. Torricelli, Francisco Penteado Crestana
Rok vydání: 2016
Předmět:
Adult
Male
Refractive error
medicine.medical_specialty
Corneal Wavefront Aberration
Mitomicina
Light
genetic structures
Mitomycin
medicine.medical_treatment
Wound healing
Administration
Ophthalmic

Spherical equivalent
Photorefractive Keratectomy
Myopia/surgery
Corneal Diseases
03 medical and health sciences
0302 clinical medicine
lcsh:Ophthalmology
Ocular straylight
Patient age
Ophthalmology
Myopia
Photorefractive keratectomy
Humans
Scattering
Radiation

Medicine
Postoperative Period
030212 general & internal medicine
business.industry
Mitomycin C
Significant difference
General Medicine
Middle Aged
medicine.disease
Ceratectomia fotorrefrativa
eye diseases
Surgery
Cross-Linking Reagents
lcsh:RE1-994
Miopia/cirurgia
030221 ophthalmology & optometry
Female
Lasers
Excimer

sense organs
Cicatrização
business
Zdroj: Arquivos Brasileiros de Oftalmologia v.79 n.2 2016
Arquivos brasileiros de oftalmologia
Conselho Brasileiro de Oftalmologia (CBO)
instacron:CBO
Arquivos Brasileiros de Oftalmologia, Vol 79, Iss 2, Pp 88-91 (2016)
ISSN: 0004-2749
DOI: 10.5935/0004-2749.20160027
Popis: Purpose: To evaluate ocular straylight before and after photorefractive keratectomy (PRK) for low myopia with and without topical mitomycin (MMC) treatment. Methods: Patients who underwent PRK for low myopia were enrolled into the study. PRK without MMC was performed in 21 eyes (12 patients), whereas PRK with topical 0.02% MMC was performed in 25 eyes (14 patients). Both groups were treated using the NIDEK EC5000 excimer laser. Measurements were performed using the C-Quant straylight meter preoperatively and at two and four months postoperatively. Results: The mean patient age was 30 ± 4 years, and the mean spherical equivalent refractive error was -2.2 ± 0.75 D. The mean preoperative intraocular straylight values were 1.07 ± 0.10 in the PRK without MMC group and 1.07 ± 0.11 log(s) in the PRK with topical MMC group. At two months after surgery, there was a decrease in mean intraocular straylight values in both groups. However, a significant difference was only reached in the PRK with MMC group [0.98 ± 0.09 log(s), p=0.002] compared with preoperative values, which was likely due to a greater scatter of measurements in the PRK without MMC group [1.03 ± 0.13 log(s), p=0.082]. At four months postoperatively, ocular straylight values were not significantly different compared with those at baseline in either the PRK without MMC group [1.02 ± 0.14 log(s), p=0.26] or in the PRK with topical MMC group [1.02 ± 0.11 log(s), p=0.13]. Conclusion: PRK for low myopia decreases ocular straylight, and MMC application further reduces straylight in the early postoperative period. However, ocular straylight values do not significantly differ at four months after surgery compared with those at baseline.
Databáze: OpenAIRE