Mathematical Modeling of Endemic Cholera Transmission
| Autor: | Dennis L. Chao |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Immunity
Herd Population level Cost-Benefit Analysis Administration Oral Health Promotion oral cholera vaccine Mass Vaccination Herd immunity law.invention Cholera Immunity law Environmental health Immunology and Allergy Medicine Humans Enteric Diseases and Nutritional Disorders: Persisting Challenges for LMICs business.industry Vaccination mathematical modeling Cholera Vaccines Models Theoretical medicine.disease Infectious Diseases Transmission (mechanics) AcademicSubjects/MED00290 Ending Cholera 2030 Mass vaccination business |
| Zdroj: | The Journal of Infectious Diseases |
| ISSN: | 1537-6613 0022-1899 |
| Popis: | Mathematical modeling can be used to project the impact of mass vaccination on cholera transmission. Here, we discuss 2 examples for which indirect protection from mass vaccination needs to be considered. In the first, we show that nonvaccinees can be protected by mass vaccination campaigns. This additional benefit of indirect protection improves the cost-effectiveness of mass vaccination. In the second, we model the use of mass vaccination to eliminate cholera. In this case, a high population level of immunity, including contributions from infection and vaccination, is required to reach the “herd immunity” threshold needed to stop transmission and achieve elimination. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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