A Review on the Effects of Supercritical Carbon Dioxide on Enzyme Activity
Autor: | Marie Zarevúcka, Zdenĕk Wimmer |
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Rok vydání: | 2010 |
Předmět: |
synthesis
Review Catalysis lcsh:Chemistry Inorganic Chemistry Enzyme activator chemistry.chemical_compound Protein structure supercritical carbon dioxide Enzyme Stability Oxidative enzyme Denaturation (biochemistry) inactivation Physical and Theoretical Chemistry lcsh:QH301-705.5 Molecular Biology Spectroscopy chemistry.chemical_classification Supercritical carbon dioxide biology Organic Chemistry Temperature General Medicine Carbon Dioxide Enzyme assay Enzymes Computer Science Applications Enzyme Activation enzyme Enzyme hydrolysis lcsh:Biology (General) lcsh:QD1-999 Biochemistry chemistry Carbon dioxide biology.protein |
Zdroj: | International Journal of Molecular Sciences, Vol 11, Iss 1, Pp 233-253 (2010) International Journal of Molecular Sciences |
ISSN: | 1422-0067 |
DOI: | 10.3390/ijms11010233 |
Popis: | Different types of enzymes such as lipases, several phosphatases, dehydrogenases, oxidases, amylases and others are well suited for the reactions in SC-CO(2). The stability and the activity of enzymes exposed to carbon dioxide under high pressure depend on enzyme species, water content in the solution and on the pressure and temperature of the reaction system. The three-dimensional structure of enzymes may be significantly altered under extreme conditions, causing their denaturation and consequent loss of activity. If the conditions are less adverse, the protein structure may be largely retained. Minor structural changes may induce an alternative active protein state with altered enzyme activity, specificity and stability. |
Databáze: | OpenAIRE |
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