Allergic sensitization related to age and clinical presentation
| Autor: | Barbara Kvenić, Monika Mačkić, Milana Đorđevski, Srđan Banac, Bojana Đokić, Tea Crnogaj |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Acute urticaria biology business.industry allergen child skin test Disease medicine.disease_cause biology.organism_classification medicine.disease Dermatology respiratory tract diseases Allergic sensitization Allergen medicine.anatomical_structure immune system diseases otorhinolaryngologic diseases Mite Medicine Medical history business alergen dijete kožni test Sensitization Asthma |
| Zdroj: | Medicina Fluminensis : Medicina Fluminensis Volume 52. Issue 4. |
| ISSN: | 0025-7729 1847-6864 1848-820X |
| DOI: | 10.21860/medflum2016_4coa |
| Popis: | Cilj: Odrediti profil alergijske senzitizacije i okidače alergijskih simptoma prema dobi djeteta i tipu alergijske bolesti. Ispitanici i metode: Restrospektivno su analizirani rezultati kožnih ubodnih testova na inhalatorne i nutritivne alergene u lokalnoj populaciji ispitanika (n=1102; dob 0-18 god; 58% (n=640) dječaka i 42% (n=462) djevojčice) koji boluju od: astme s pridruženim alergijskim rinitisom ili rinokonjunktivitisom 29% (n=323), alergijskog rinitisa 24% (n=269), atopijskog ekcema 21% (n=226), alergijskog rinokonjunktivitisa 13% (n=148), astme 8% (n=85), te akutne alergijske urtikarije 5% (n=51). Podaci o neposredno zamijećenim okidačima alergijskih simptoma dobiveni su analizom anamnestičkih podataka. Rezultati: U ispitanika dojenačke dobi značajno dominira senzitizacija na nutritivne alergene (P Aim: To determine sensitization profile and allergic triggers related to allergic disease and the age of the child. Subjects and methods: Results of skin prick tests were retrospectively analyzed to inhalational and nutritive allergens in the local population of subjects (n=1102; age 0-18 years; 58% (n=640) boys and 42% (n=462) girls) who suffer from asthma associated with allergic rhinitis or rhinoconjunctivitis 29% (n=323), allergic rhinitis 24% (n=269), atopic eczema 21% (n=226), allergic rhinoconjunctivitis 13% (n=148), allergic asthma 8% (n=85) and acute allergic urticaria 5% (n=51). Data considering diretcly notable triggers of allergic symptoms were obtained from medical history. Results: Sensitization to nutritive allergens dominates in infants (P=0.001). Sensitization to inhalant allergens has siginificant frequency in children after three years of age Sensitization to mite allergens and hairy pets appeared firstly (P=0.003). Sensitization to pollen becomes significant at school age. In subjects with asthma and allergic rhinitis dominate sensitization to inhalant allergens, mostly on mites (P=0.007), except in allergic rhinoconjunctivitis where sensitization to grass pollen is dominant. Subjects with eczema and acute urticaria are mostly sensitized to nutritive allergens such as eggs, nuts and cow's milk. However, sensitization to mites seems to be also important. Allergens are seldom observed as direct triggers of allergic symptoms. In case they are mostly associated with pollination, with hairy pets and with the consumption of eggs. Conclusion: The results are of practical importance for everyday evaluation of allergic sensitization in local population of patients. They can help in the rational selection of current and relevant allergens for skin prick testing taking care of the child's age and its allergic disease or symptoms. |
| Databáze: | OpenAIRE |
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