| Autor: |
Laggner, Maria, Gugerell, Alfred, Bachmann, Christiane, Hofbauer, Helmut, Vorstandlechner, Vera, Seibold, Marcus, Ghazaleh Gouya Lechner, Peterbauer, Anja, Madlener, Sibylle, Demyanets, Svitlana, Sorgenfrey, Dirk, Ostler, Tobias, Erb, Michael, Mildner, Michael, Ankersmit, Hendrik |
| Rok vydání: |
2020 |
| DOI: |
10.6084/m9.figshare.11507904 |
| Popis: |
Additional file 1: Figure S1. Cytokine profiling. Figure S2. Concentrations of (a) PAI-1 and (b) MMP9 in the secretomes of individual donors. Protein concentrations were determined for secretomes prior to pooling, lyophilization, and terminal sterilization. Each dot represents one donor. Horizontal lines indicate medians. PAI-1, plasminogen activator inhibitor 1; MMP9, matrix metallopeptidase. Figure S3. Concentrations of (a) PAI-1 and (b) MMP9 in small batches of PBMC secretomes (12 donors) compared to PBMCsec 1 (open dots) and PBMCsec 2 (black dots). Large batches contain secretomes of 96 – 120 donors. Open dots represent small batches pooled for PBMCsec 1, while black dots denote small batches used for PBMCsec 2. Horizontal lines indicate medians. PAI-1, plasminogen activator inhibitor 1; MMP9, matrix metallopeptidase. Figure S4. Potency of secretomes obtained from individual PBMC donors. Figure S5. (a) AP-1 promotor activity and (b) HSP27 phosphorylation in small and large secretome batches. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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