Chromatin remodeling complexes are involvesd in the regulation of ethanol production during static fermentation in budding yeast
| Autor: | Hongbo Yan, Jian Liu, Tianshu Fang, Linghuo Jiang, Weipeng Chen, Gaozhen Li |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
Saccharomyces cerevisiae Proteins Chromosomal Proteins Non-Histone Saccharomyces cerevisiae Ethanol fermentation Biology 01 natural sciences Chromatin remodeling 03 medical and health sciences Transcription (biology) Gene Expression Regulation Fungal Genetics Basic Helix-Loop-Helix Transcription Factors Ethanol fuel Transcription factor 030304 developmental biology 0303 health sciences Ethanol biology.organism_classification Chromatin Assembly and Disassembly Yeast Cell biology Repressor Proteins Basic-Leucine Zipper Transcription Factors Fermentation 010606 plant biology & botany Transcription Factors |
| Zdroj: | Genomics. 112(2) |
| ISSN: | 1089-8646 |
| Popis: | The budding yeast Saccharomyces cerevisiae remains a central position among biofuel-producing organisms. However, the gene expression regulatory networks behind the ethanol fermentation is still not fully understood. Using a static fermentation model, we have examined the ethanol yields on biomass of deletion mutants for all yeast nonessential genes encoding transcription factors and their related proteins in the yeast genome. A total of 20 (about 10%) transcription factors are identified to be regulators of ethanol production during fermentation. These transcription factors are mainly involved in cell cycling, chromatin remodeling, transcription, stress response, protein synthesis and lipid synthesis. Our data provides a basis for further understanding mechanisms regulating ethanol production in budding yeast. |
| Databáze: | OpenAIRE |
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