Thermodynamic Study on the Interaction of Ampicillin and Amoxicillin with Ca2+ in Aqueous Solution at Different Ionic Strengths and Temperatures
| Autor: | Claudia Foti, Ottavia Giuffrè, Silvio Sammartano, Sara Angowska |
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| Rok vydání: | 2019 |
| Předmět: |
Aqueous solution
Chemistry Ligand General Chemical Engineering Inorganic chemistry Potentiometric titration Ionic bonding Chemistry (all) Chemical Engineering (all) 02 engineering and technology General Chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences Metal 020401 chemical engineering Ionic strength Stability constants of complexes visual_art visual_art.visual_art_medium 0204 chemical engineering |
| Zdroj: | Journal of Chemical & Engineering Data. 64:800-809 |
| ISSN: | 1520-5134 0021-9568 |
| DOI: | 10.1021/acs.jced.8b01081 |
| Popis: | A potentiometric and UV spectrophotometric study on Ca2+–ampicillin and −amoxicillin systems in NaCl aqueous solution is reported. The potentiometric investigation was carried out at different ionic strengths, I = (0.15 to 1) mol kg–1, and temperatures, T = (288.15 to 310.15) K. The most reliable speciation models include two species, namely, CaLH and CaL for the Ca2+–ampicillin system and CaLH2 and CaLH for the Ca2+–amoxicillin system. The spectrophotometric results obtained for both of the systems are fully consistent with potentiometric ones, confirming the formation as well as the stability of the complex species. The dependence of formation constants of the species on ionic strength over the range I = (0.15 to 1) mol kg–1 in NaCl and on temperature over the range T = (288.15 to 310.15) K is also reported. pL0.5 empirical parameter (i.e., the concentration of ligand required to bind 50% of the metal cation present in the trace) was employed to evaluate the ability of both of the ligands to sequester C... |
| Databáze: | OpenAIRE |
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