Disparate Effects of Left Ventricular Geometry and Obesity on Mortality in Patients With Preserved Left Ventricular Ejection Fraction
| Autor: | Franz H. Messerli, Hector O. Ventura, Gustavo A. Cardenas, Mandeep R. Mehra, Richard V. Milani, Carl J. Lavie |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Hemodynamics Concentric hypertrophy Muscle hypertrophy Risk Factors Internal medicine Prevalence Humans Medicine Obesity Risk factor Ventricular remodeling Aged Retrospective Studies Ultrasonography Ejection fraction Ventricular Remodeling business.industry Stroke Volume Stroke volume Middle Aged Prognosis medicine.disease Cardiology Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business Obesity paradox |
| Zdroj: | The American Journal of Cardiology. 100:1460-1464 |
| ISSN: | 0002-9149 |
| DOI: | 10.1016/j.amjcard.2007.06.040 |
| Popis: | Left ventricular (LV) geometry predicts cardiovascular events. Although obesity is a risk factor for cardiovascular diseases, studies have noted a paradox regarding obesity and prognosis. To our knowledge no studies have determined the impact of obesity on LV geometry as well as mortality in patients with preserved ejection fraction. We evaluated 30,920 patients with preserved ejection fraction, including 11,792 obese patients as well as 19,128 nonobese patients to determine the impact of 4 LV geometric patterns, including normal structure, concentric remodeling (CR), as well as eccentric or concentric hypertrophy and obesity on mortality during an average follow-up of 3.2 ± 1.4 years. Abnormal LV geometry occurred more commonly in obese than nonobese patients (49% vs 44%, p |
| Databáze: | OpenAIRE |
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