Epidemic myalgia in adults associated with human parechovirus type 3 infection, Yamagata, Japan, 2008
Autor: | Tetsuya Mizutani, Yoshikazu Yahata, Takeo Kato, Tatsuya Ikeda, Tadayuki Ahiko, Katsumi Mizuta, Makoto Kuroda, Chieko Abiko, Masahiro Noda, Masayuki Kurimura, Hirokazu Kimura, Toru Kawanami, Tsuyoshi Sekizuka, Yoko Aoki |
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Rok vydání: | 2012 |
Předmět: |
myalgia
Male Pediatrics Epidemiology viruses lcsh:Medicine Parechovirus Disease Picornaviridae Serology Disease Outbreaks HPeV Japan Sore throat adults HPeV3 Myositis Phylogeny biology Human parechovirus Middle Aged humanities Infectious Diseases RNA Viral Female medicine.symptom epidemic myalgia Microbiology (medical) Adult medicine.medical_specialty education Molecular Sequence Data Pleurodynia Epidemic Genome Viral human parechovirus lcsh:Infectious and parasitic diseases children medicine Humans lcsh:RC109-216 Serotyping Aged Picornaviridae Infections business.industry Research lcsh:R Outbreak medicine.disease biology.organism_classification Immunology business myositis |
Zdroj: | Emerging Infectious Diseases Emerging Infectious Diseases, Vol 18, Iss 11, Pp 1787-1793 (2012) |
ISSN: | 1080-6059 |
Popis: | This virus typically causes illness in young children but was found to be associated with illness in adults. Human parechovirus has rarely been shown to cause clinical disease in adults. During June–August 2008, a total of 22 adults sought treatment at Yonezawa City Hospital in Yamagata, Japan, for muscle pain and weakness of all limbs; most also had fever and sore throat. All patients received a clinical diagnosis of epidemic myalgia; clinical laboratory findings suggested an acute inflammatory process. Laboratory confirmation of infection with human parechovirus type 3 (HPeV3) was made for 14 patients; we isolated HPeV3 from 7 patients, detected HPeV3 genome in 11, and observed serologic confirmation of infection in 11. Although HPeV3 is typically associated with disease in young children, our results suggest that this outbreak of myalgia among adults was associated with HPeV3 infection. Clinical consideration should be given to HPeV3 not only in young children but also in adults when an outbreak occurs in the community. |
Databáze: | OpenAIRE |
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