Possible health effects of high manganese concentration in drinking water
| Autor: | Nicolas Makris, Theodore Papapetropoulos, B S Mary Prinou, Xenophon G. Kondakis, B S Michael Leotsinidis |
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| Rok vydání: | 1989 |
| Předmět: |
Central Nervous System
Male chemistry.chemical_element Manganese Biology Sampling Studies Toxicology Animal science Sex Factors Water Supply Environmental Chemistry Humans Manganese Poisoning Water Pollutants General Environmental Science Aged Neurologic Examination Hydrogen compounds Greece Sex dependence Public Health Environmental and Occupational Health Middle Aged Biological materials Geographic distribution chemistry Toxicity Chronic Disease Female Water Pollutants Chemical Hair |
| Zdroj: | Archives of environmental health. 44(3) |
| ISSN: | 0003-9896 |
| Popis: | Three areas in the same region of northwest Peloponnesos, Greece, that had varying concentrations of manganese (Mn) in drinking water were selected for study. The Mn concentrations in areas A, B, and C were 3.6-14.6 micrograms/l, 81.6-252.6 micrograms/l, and 1 800-2 300 micrograms/l, respectively. A random sample (62 in area A, 49 in area B, and 77 in area C) of males and females who were at least 50 y of age were submitted to a thorough neurological examination and their whole-blood Mn and hair Mn concentrations were determined. Although all areas were similar with respect to social and dietary characteristics, significant differences were observed for prevalence of chronic manganese poisoning (CMnP) symptoms and hair Mn concentration. The means (both sexes) of neurological scores were 2.7, 3.9, and 5.2, respectively, for areas A, B, and C (Kruskal-Wallis, chi 2 = 6.44, 2 df, p less than .05 for males; chi 2 = 7.8, 2 df, p less than .05 for females). Hair Mn concentrations were also significantly different, the means for which were 3.51, 4.49, and 10.99 micrograms/g dry weight, respectively (both sexes [p less than .001 for each sex separately]). These results indicate that progressive increases of Mn concentration in drinking water are associated with progressively higher prevalences of neurological signs of CMnP and Mn concentration in hair of older persons. |
| Databáze: | OpenAIRE |
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