Surgical and non-surgical management of thoracic and cervical paraganglioma

Autor: Marta Araujo-Castro, Sandra Redondo López, Eider Pascual-Corrales, Rubén Polo López, Teresa Alonso-Gordoa, Javier Molina-Cerrillo, Nicolás Moreno Mata, Usue Caballero Silva, Rafael Barberá Durbán
Rok vydání: 2022
Předmět:
Zdroj: Annales d'Endocrinologie.
ISSN: 0003-4266
DOI: 10.1016/j.ando.2022.10.013
Popis: Thoracic and cervical paraganglioma (PGL) is a rare neuroendocrine tumor arising from chromaffin cells of the neural crest progenitors located outside the adrenal gland. We describe our current protocol as a multidisciplinary team for the management of cervical and thoracic PGL. Surgery is generally considered the treatment of choice as it offers the best chance for cure. For resection of thoracic PGL, video-assisted thoracoscopic surgery (VATS) is the main surgical approach, while open thoracotomy is preferred in case of tumor6cm, lacking confirmation of a plane of separation with adjacent structures, or with technical difficulties during VATS. In cervical PGL, the surgical approach should be individualized according to location, mainly based on the Glasscock-Jackson and the Fisch-Mattox classifications. Surgery is the treatment of choice for most cervical and thoracic PGLs, but radiotherapy or observation could be more suitable options in unresectable cervical and thoracic PGL or when resection has been incomplete.
Databáze: OpenAIRE