DoRGaN: Development of Quality Assurance and Quality Control Systems for High Dose Rate Brachytherapy Based on GaN Dosimetry Probes
| Autor: | Guo-Neng Lu, L. Gindraux, Pierrick Guiral, Patrice Jalade, Jean-Marc Galvan, R. Wang, Patrick Pittet |
|---|---|
| Přispěvatelé: | INL - Conception de Systèmes Hétérogènes (INL - CSH), Institut des Nanotechnologies de Lyon (INL), École Centrale de Lyon (ECL), Université de Lyon-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-École supérieure de Chimie Physique Electronique de Lyon (CPE)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS)-École Centrale de Lyon (ECL), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Centre National de la Recherche Scientifique (CNRS), Dosilab SARL, Dosilab, Service de Radiophysique et Radiovigilance, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon (HCL) |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Computer science business.industry Biomedical Engineering Biophysics Quality control Treatment verification High-Dose Rate Brachytherapy Imaging phantom 030218 nuclear medicine & medical imaging [SPI]Engineering Sciences [physics] 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Large dose medicine Dosimetry Medical physics business In vivo dosimetry Quality assurance ComputingMilieux_MISCELLANEOUS |
| Zdroj: | Innovation and Research in BioMedical engineering Innovation and Research in BioMedical engineering, Elsevier Masson, 2018, 39 (4), pp.279-290. ⟨10.1016/j.irbm.2018.04.005⟩ |
| ISSN: | 1959-0318 |
| DOI: | 10.1016/j.irbm.2018.04.005 |
| Popis: | Background Safe High Dose Rate Brachytherapy (HDR-BT) requires quality assurance/quality control (QA/QC) according to IPEM and ESTRO recommendations. Recent advances in real-time dosimetry and related developments of QA, QC and in vivo dosimetry (IVD) systems have offered new possibilities for effective independent treatment verification, and thus for improving the patient safety. Contributions This paper briefly reports the state of the art of different QA and QC approaches and systems. It also presents our related studies, carried out within the framework of DoRGaN research project, which have led to two proposed instruments: a QA pretreatment instrumented phantom and a QC gynecological applicator. Both systems implement a real-time dwell-source distance-measuring approach using multiple Gallium Nitride (GaN) dosimetry probes. First prototypes have been designed and tested. Their characteristics (including those of the employed GaN probes) are evaluated in comparison with the state of the art. Conclusion For developing systems for HDR-BT, the GaN probe has been shown to meet requirements for high sensitivity, high measurement rate, small response anisotropy and large dose measurement range. The proposed QA instrumented phantom has comparable or better characteristics when compared with diode-based and Al2O3:C-based systems. The other QC gynecological applicator has higher time and spatial resolutions than the state-of-the-art IVD systems, which proves that it is suitable for real-time monitoring of HDR-BT physical parameters. |
| Databáze: | OpenAIRE |
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