The LungVision navigational platform for peripheral lung nodule biopsy and the added value of cryobiopsy

Autor: Moshe Heching, Shimon Izhakian, Barak Pertzov, Evgeni Gershman, Dror Rosengarten, Shai Moshe Amor, Mordechai R. Kramer
Rok vydání: 2021
Předmět:
0301 basic medicine
Pulmonary and Respiratory Medicine
Image-Guided Biopsy
Male
medicine.medical_specialty
bronchoscopy
medicine.medical_treatment
cryobiopsy
Lesion
03 medical and health sciences
0302 clinical medicine
Bronchoscopy
Interquartile range
Biopsy
medicine
Humans
Sampling (medicine)
Prospective Studies
navigation
RC254-282
Aged
Lung
medicine.diagnostic_test
business.industry
peripheral pulmonary nodule
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Solitary Pulmonary Nodule
General Medicine
Original Articles
Middle Aged
medicine.disease
Chest tube
030104 developmental biology
medicine.anatomical_structure
Oncology
Pneumothorax
030220 oncology & carcinogenesis
Fluoroscopy
diagnostic yield
Multiple Pulmonary Nodules
Female
Original Article
Radiology
medicine.symptom
business
Zdroj: Thoracic Cancer
Thoracic Cancer, Vol 12, Iss 13, Pp 2007-2012 (2021)
ISSN: 1759-7714
Popis: Background The LungVision system is a novel augmented‐fluoroscopy‐based real‐time navigation and guidance technology for bronchoscopy that can be integrated with any standard biopsy tool, including the cryoprobe, to enable real‐time visualization and localization of pulmonary nodules. Objectives To evaluate the diagnostic yield and safety among patients undergoing peripheral pulmonary nodule biopsy with the LungVision system. Methods This prospective, single‐center study was conducted at Rabin Medical Center in Israel. All patients that underwent peripheral pulmonary nodule biopsy with the LungVision system from January 2016 to August 2020 were included. All procedures were performed under moderate sedation. The primary outcome was tissue diagnosis by either identification of malignant cells or benign diagnosis. Secondary outcomes were safety and the added value of cryobiopsy. Results Sixty‐three procedures were performed during the study period. Median lesion size (interquartile range) was 25.0 mm (18–28 mm). The diagnostic yield overall was 27/33 (81.8%) and for lesions smaller than 20 mm was 13/18 (72.2%). In nine cases the transbronchial cryobiopsy showed tissue with malignant cells that were not found in any other biopsy material taken with other sampling tools. One patient was treated with a chest tube for a pneumothorax. No other major complications were reported. Conclusions The LungVision system showed good feasibility and safety for peripheral pulmonary nodule biopsy. The system is compatible with all biopsy tools, including the cryoprobe. Randomized controlled trials are needed to accurately ascertain its diagnostic yield.
The LungVision fluoroscopy‐based navigation and guidance technology for bronchoscopic biopsy of peripheral pulmonary nodules is safe and effective.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje