Operationalizing a frailty index using routine blood and urine tests
| Autor: | Julia Isabel Ritt, Cornel C. Sieber, Jakob Jäger, Karl-Günter Gaßmann, Martin Ritt |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Gerontology
Male medicine.medical_specialty Frail Elderly Frailty Index Urine risk stratification Urinalysis Age and sex older people 03 medical and health sciences 0302 clinical medicine Risk Factors Secondary analysis Internal medicine medicine Humans 030212 general & internal medicine Prospective Studies hospital Prospective cohort study Geriatric Assessment Original Research Aged Aged 80 and over geriatric wards Hematologic Tests Frailty business.industry Geriatric assessment General Medicine mortality Frailty phenotype ROC Curve Clinical Interventions in Aging Female Geriatrics and Gerontology Blood parameters business 030217 neurology & neurosurgery |
| Zdroj: | Clinical Interventions in Aging |
| ISSN: | 1178-1998 1176-9092 |
| Popis: | Martin Ritt,1,2 Jakob Jäger,2 Julia Isabel Ritt,2 Cornel Christian Sieber,1,3 Karl-Günter Gaßmann1,2 1Institute for Biomedicine of Ageing (IBA), Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Nuremberg, Germany; 2Department of Internal Medicine III (Medicine of Ageing), Geriatrics Center Erlangen, Hospital of the Congregation of St Francis Sisters of Vierzehnheiligen, Erlangen, Germany; 3Department of General Internal Medicine and Geriatrics, Hospital of the Order of St John of God, Regensburg, Germany Background: Uncomplicated frailty instruments are desirable for use in a busy clinical setting. The aim of this study was to operationalize a frailty index (FI) from routine blood and urine tests, and to evaluate the properties of this FI compared to other frailty instruments.Materials and methods: We conducted a secondary analysis of a prospective cohort study on 306 patients aged ≥65 years hospitalized on geriatric wards. An FI comprising 22 routine blood parameters and one standard urine parameter (FI-Lab), a 50-item FI based on a comprehensive geriatric assessment (FI-CGA), a combined FI (FI-combined [items from the FI-Lab + others from the FI-CGA]), the Clinical Frailty Scale, rule-based frailty definition, and frailty phenotype were operationalized from data obtained during patients’ hospital stays (ie, before discharge [baseline examination]). Follow-up data were obtained up to 1 year after the baseline examination.Results: The mean FI-Lab score was 0.34±15, with an upper limit of 0.74. The FI-Lab was correlated with all the other frailty instruments (all P |
| Databáze: | OpenAIRE |
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