[Ir(P−OP)]-Catalyzed Asymmetric Hydrogenation of Diversely Substituted C═N-Containing Heterocycles

Autor:	José Luis Núñez-Rico, Anton Vidal-Ferran
Rok vydání:	2013
Předmět:	Molecular Structure Benzoxazinones Chemistry Organic Chemistry Asymmetric hydrogenation Enantioselective synthesis chemistry.chemical_element Stereoisomerism Iridium Heterocyclic Compounds 2-Ring Biochemistry Catalysis Molecule Organic chemistry Hydrogenation Physical and Theoretical Chemistry
Zdroj:	Organic Letters. 15:2066-2069
ISSN:	1523-7052 1523-7060
Popis:	Iridium(I) complexes of enantiomerically pure phosphine-phosphite ligands ([Ir(Cl)(cod)(P-OP)]) efficiently catalyze the enantioselective hydrogenation of diverse C═N-containing heterocyclic compounds (benzoxazines, benzoxazinones, benzothiazinones, and quinoxalinones; 25 examples, up to 99% ee). A substrate-to-catalyst ratio as high as 2000:1 was reached.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3445ebd9503fec700bba1d83d21ae533 https://doi.org/10.1021/ol400854a Zobrazit plný text záznamu