Hypertension, genotype and oral contraceptives
| Autor: | Paolo Mulatero, Morra di Cella S, Franco Veglio |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
Genotype Physiology Disease Pathogenesis Renin-Angiotensin System Epidemiology Genetics medicine Genetic predisposition Animals Humans Genetic Predisposition to Disease Oligonucleotide Array Sequence Analysis Pharmacology Estroprogestin Polymorphism Genetic business.industry Gene Expression Profiling Pathophysiology Blood pressure Drug Design Hypertension Molecular Medicine business Contraceptives Oral |
| Popis: | Oral contraceptive-induced hypertension (OCIH) is a well-recognized phenomenon characterized by an increase in blood pressure levels after beginning estroprogestin therapy and a reduction to normal levels within 1 year after suspension of the therapy. The pathophysiology of this condition is still not understood: several lines of evidence indicate a role for a genetic susceptibility to the development of this disease. In this article, the epidemiology and the pathogenesis of OCIH are reviewed with particular emphasis on the genetic influence in light of the most recent studies in this field. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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