Differentiated thyroid carcinomas and regional metastases
| Autor: | Jasna Mihailovic, Katarina Kermeci, Silvija M. Popadić, Ljubomir Stefanovic, Milica Đ. Malešević, Dolores Srbovan |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Oncology
medicine.medical_specialty medicine.medical_treatment carcinoma lcsh:RC254-282 Gastroenterology Thyroid carcinoma papillary follicular Internal medicine Follicular phase Carcinoma medicine lymphatic metastasis Chemotherapy thyroid neoplasms business.industry Thyroid Hematology lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Primary tumor medicine.anatomical_structure Hormonal therapy Lymph business |
| Zdroj: | Archive of Oncology, Vol 11, Iss 3, Pp 185-185 (2003) |
| ISSN: | 1450-9520 0354-7310 |
| DOI: | 10.2298/aoo0303185s |
| Popis: | Background: Aim of the study was to determine the frequency of regional nodal metastases (N1) of differentiated thyroid carcinomas (DTC), to analyze the modes of treatment, course of disease, and outcome. Methods: In Department of Nuclear Medicine in Sremska Kamenica, 363 DTC patients were treated from 1977 to the end of 2000. Nodal metastases had 182 patients most of them were followed to the end of 2000. Methods: All patients with N1 were treated surgically (operation of thyroid gland was done in all patients, surgical treatment of lymph nodes in 80.2% of them), afterwards by radioiodine and long-life by hormonal therapy; external beam therapy was applied in 9.9% of patients, chemotherapy in 1.6% of patients. The range of follow-up was from 2 months to 24.2 years, the mean 4.7 years. Results Nodal metastases were detected first, before primary tumor, in 21.9% patients, and simultaneously in 63.2% patients. They appeared subsequently after detection and initial treatment of primary tumor in 14.8% patients the incomplete initial therapy in this subgroup of patients was more frequent than complete therapy (p |
| Databáze: | OpenAIRE |
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