Cardiac arrhythmias in hospitalized patients with COVID-19: A prospective observational study in the western United States

Autor: Richard Shelton, Michael Shehata, Eugenio Cingolani, Xunzhang Wang, Eduardo Marbán, Sumeet S. Chugh, Archana Ramireddy, Jae Hyung Cho, Ali Namazi, Ashkan Ehdaie
Přispěvatelé: Tolkacheva, Elena G
Rok vydání: 2020
Předmět:
Tachycardia
Male
Viral Diseases
Epidemiology
Arrhythmias
030204 cardiovascular system & hematology
Cardiovascular
Ventricular tachycardia
Biochemistry
Electrocardiography
0302 clinical medicine
Medical Conditions
Heart Rate
Risk Factors
Atrial Fibrillation
Medicine and Health Sciences
Cardiac Arrest
Telemetry
030212 general & internal medicine
Hospital Mortality
Prospective Studies
education.field_of_study
Multidisciplinary
medicine.diagnostic_test
Incidence
Atrial fibrillation
Troponin
Hospitalization
Myocarditis
Heart Disease
Infectious Diseases
Ventricular Fibrillation
Cardiology
cardiovascular system
Medicine
Female
medicine.symptom
Cardiac
Arrhythmia
Cancer Epidemiology
Research Article
medicine.medical_specialty
Monitoring
General Science & Technology
Sinus tachycardia
Science
Population
Risk Assessment
03 medical and health sciences
Clinical Research
Internal medicine
medicine
Humans
Physiologic
education
Aged
Monitoring
Physiologic
business.industry
Ventricular
COVID-19
Biology and Life Sciences
Proteins
Arrhythmias
Cardiac
Covid 19
medicine.disease
United States
Cytoskeletal Proteins
Good Health and Well Being
Ventricular fibrillation
Tachycardia
Ventricular
business
Zdroj: PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0244533 (2020)
PloS one, vol 15, iss 12
ISSN: 1932-6203
Popis: Arrhythmias have been reported frequently in COVID-19 patients, but the incidence and nature have not been well characterized. Patients admitted with COVID-19 and monitored by telemetry were prospectively enrolled in the study. Baseline characteristics, hospital course, treatment and complications were collected from the patients’ medical records. Telemetry was monitored to detect the incidence of cardiac arrhythmias. The incidence and types of cardiac arrhythmias were analyzed and compared between survivors and non-survivors. Among 143 patients admitted with telemetry monitoring, overall in-hospital mortality was 25.2% (36/143 patients) during the period of observation (mean follow-up 23.7 days). Survivors were less tachycardic on initial presentation (heart rate 90.6 ± 19.6 vs. 99.3 ± 23.1 bpm, p = 0.030) and had lower troponin (peak troponin 0.03 vs. 0.18 ng/ml. p = 0.004), C-reactive protein (peak C-reactive protein 97 vs. 181 mg/dl, p = 0.029), and interleukin-6 levels (peak interleukin-6 30 vs. 246 pg/ml, p = 0.003). Sinus tachycardia, the most common arrhythmia (detected in 39.9% [57/143] of patients), occurred more frequently in non-survivors (58.3% vs. 33.6% in survivors, p = 0.009). Premature ventricular complexes occurred in 28.7% (41/143), and non-sustained ventricular tachycardia in 15.4% (22/143) of patients, with no difference between survivors and non-survivors. Sustained ventricular tachycardia and ventricular fibrillation were not frequent (seen only in 1.4% and 0.7% of patients, respectively). Contrary to reports from other regions, overall mortality was higher and ventricular arrhythmias were infrequent in this hospitalized and monitored COVID-19 population. Either disease or management-related factors could explain this divergence of clinical outcomes, and should be urgently investigated.
Databáze: OpenAIRE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje