Discovery of Resorcinol-Based Polycyclic Structures as Tyrosinase Inhibitors for Treatment of Parkinson’s Disease

Autor:	Qi Li, Jun Mo, Baichen Xiong, Qinghong Liao, Ying Chen, Yuanyuan Wang, Shuaishuai Xing, Siyu He, Weiping Lyu, Ning Zhang, Haopeng Sun
Rok vydání:	2021
Předmět:	Monophenol Monooxygenase Physiology Cognitive Neuroscience Parkinson Disease Resorcinols Cell Biology General Medicine Biochemistry Mice Inbred C57BL Disease Models Animal Mice Neuroprotective Agents Parkinsonian Disorders 1-Methyl-4-phenyl-1 2 3 6-tetrahydropyridine Animals
Zdroj:	ACS Chemical Neuroscience. 13:81-96
ISSN:	1948-7193
DOI:	10.1021/acschemneuro.1c00560
Popis:	Tyrosinase is involved in the synthesis of neuromelanin in the substantia nigra, which is closely correlated with the pathogenesis of Parkinson's disease. Herein, we identified
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342136b01fd4a697b90fa25c0184550e https://doi.org/10.1021/acschemneuro.1c00560 Zobrazit plný text záznamu