Potential Beneficial Effects of Dietary Protein Supplementation and Exercise on Functional Capacity in a Pilot Study of Individuals with Heart Failure with Preserved Ejection Fraction
| Autor: | Amy Schrader, Robert R. Wolfe, Jeanne Y. Wei, Sakeena Raza, Kellie S. Coleman, Amanda M. Dawson, Amanda K. Pangle, Gohar Azhar |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
obesity heart failure 030204 cardiovascular system & hematology lcsh:Geriatrics Article dietary supplements 03 medical and health sciences 0302 clinical medicine Quality of life Internal medicine medicine 030212 general & internal medicine Beneficial effects exercise therapy business.industry aging Exercise therapy medicine.disease Obesity lcsh:RC952-954.6 Dietary protein Physical performance Heart failure Cardiology Geriatrics and Gerontology Heart failure with preserved ejection fraction business |
| Zdroj: | Gerontology and Geriatric Medicine, Vol 6 (2020) Gerontology and Geriatric Medicine |
| ISSN: | 2333-7214 |
| Popis: | Approximately half of heart failure patients in the US have heart failure with preserved ejection fraction (HFpEF). HFpEF impairs physical performance and thus reduces quality of life. Increasing dietary protein intake can increase lean body mass and physical performance in healthy elderly individuals, but the effect of a high-quality protein supplement, with or without a structured exercise program, has not been investigated in HFpEF patients. Twenty-three obese elderly HFpEF patients with grade 1 or 2 diastolic dysfunction were randomized into three groups: control, protein supplementation alone, and protein plus exercise. Protein supplementation involved providing sufficient whey protein so that total intake was 1.2 g protein/kg/day. The exercise intervention was 2 days of hydrotherapy and 1 day of gym sessions per week under supervision of a fitness expert. Physical parameters and functional tests were performed at baseline and at 12 weeks. Protein supplementation alone failed to improve physical performance. However, when combined with light exercise, there was significant improvement in some (6-minute walk, 10 m walking speed, quadriceps strength), but not all, physical function measurements. The results of this pilot study suggest that further exploration of potential interactive effects between protein supplementation and light exercise in individuals with HFpEF is warranted. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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