Streptococcal group A carbohydrate has properties of both a thymus-independent (TI-2) and a thymus-dependent antigen

Autor:	Briles, D. E., Moon Nahm, Marion, T. N., Perlmutter, R. M., Davie, J. M.
Rok vydání:	1982
Předmět:	Immunology Immunology and Allergy
Zdroj:	Scopus-Elsevier
ISSN:	1550-6606 0022-1767
Popis:	Streptococcal group A carbohydrate, which elicits mouse antibody of primarily the IgM and IgG3 isotypes, is relatively nonimmunogenic in nu/nu or xid mice, and thus appears to be a type of TD-2 antigen. The TD-2 antigens described previously have been proteins that elicit IgG antibody primarily of the IgG1 and IgG2 isotypes. Our findings indicate that TD-2 properties may also be a characteristic of at least some carbohydrate antigens that can elicit IgG antibody predominantly of the IgG3 class.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34177896932b1a209141996ac7764510 https://doi.org/10.4049/jimmunol.128.5.2032 Zobrazit plný text záznamu