Can low-dose CT with iterative reconstruction reduce both the radiation dose and the amount of iodine contrast medium in a dynamic CT study of the liver?
| Autor: | Yuki Kagawa, Masahiro Okada, Syojiro Hidaka, Mitsuru Matsuki, Masakatsu Tsurusaki, Hiroto Takahashi, Takamichi Murakami, Tomoko Hyodo |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Carcinoma Hepatocellular media_common.quotation_subject chemistry.chemical_element Contrast Media Iterative reconstruction Iodine Radiation Dosage Sensitivity and Specificity Radiation Protection Low dose ct Medicine Contrast (vision) Humans Radiology Nuclear Medicine and imaging media_common Aged Aged 80 and over Observer Variation business.industry Radiation dose Liver Neoplasms Reproducibility of Results General Medicine Middle Aged Radiographic Image Enhancement Contrast medium chemistry Radiographic Image Interpretation Computer-Assisted Female Tomography Dynamic ct Radiology business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | European journal of radiology. 83(4) |
| ISSN: | 1872-7727 |
| Popis: | To investigate whether low-dose dynamic CT of the liver with iterative reconstruction can reduce both the radiation dose and the amount of contrast medium.This study was approved by our institutional review board. 113 patients were randomly assigned to one of two groups. Group A/group B (fifty-eight/fifty-five patients) underwent liver dynamic CT at 120/100 kV, with 0/40% adaptive statistical iterative reconstruction (ASIR), with a contrast dose of 600/480 mg I/kg, respectively. Radiation exposure was estimated based on the manufacturer's phantom data. The enhancement value of the hepatic parenchyma, vessels and the tumor-to-liver contrast of hepatocellular carcinomas (HCCs) were compared between two groups. Two readers independently assessed the CT images of the hepatic parenchyma and HCCs.The mean CT dose indices: 6.38/4.04 mGy, the dose-length products: 194.54/124.57 mGy cm, for group A/group B. The mean enhancement value of the hepatic parenchyma and the tumor-to-liver contrast of HCCs with diameters greater than 1cm in the post-contrast all phases did not differ significantly between two groups (P0.05). The enhancement values of vessels in group B were significantly higher than that in group A in the delayed phases (P0.05). Two reader's confidence levels for the hepatic parenchyma in the delayed phases and HCCs did not differ significantly between the groups (P0.05).Low-dose dynamic CT with ASIR can reduce both the radiation dose and the amount of contrast medium without image quality degradation, compared to conventional dynamic CT without ASIR. |
| Databáze: | OpenAIRE |
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