Glucose-6-phosphate dehydrogenase deficiency and idiopathic presenile cataract in Dalmatia, Croatia
| Autor: | Ivna Plestina-Borjan, Joško Markić, Jaksa Zanchi, Vjekoslav Krzelj, Venera Lakos, Ksenija Karaman |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Presenile cataracts Croatia G6PD activity Population Prevalence Cataract Cataracts hemic and lymphatic diseases Internal medicine parasitic diseases medicine Humans Risk factor education education.field_of_study Phacoemulsification business.industry glucose-6-phosphate dehydrogenase deficiency cataracts nutritional and metabolic diseases General Medicine Middle Aged medicine.disease Ophthalmology Endocrinology Glucosephosphate Dehydrogenase Deficiency business Glucose-6-phosphate dehydrogenase deficiency |
| Zdroj: | Canadian journal of ophthalmology. Journal canadien d'ophtalmologie. 42(6) |
| ISSN: | 0008-4182 |
| Popis: | Background: Impaired activity of the enzyme glucose-6-phosphate dehydrogenase (G6PD) has been suggested as a risk factor in cataractogenesis. The aim of this study was to determine the G6PD activity level in 89 male subjects of Dalmatian origin with idiopathic presenile cataracts. Methods: G6PD activity was determined by a quantitative spectrophotometric method. Results: Of 89 males with presenile cataracts only one (1.1%) had G6PD deficiency. The G6PD deficiency prevalence rate among males with presenile cataracts is not significantly different ( p > 0.05) from the prevalence of G6PD deficiency in the general population of Dalmatia (0.75% among men). Interpretation: The results of this study suggest that G6PD deficiency does not represent a pathogenetic factor in presenile cataract, at least not in the population of the southern part of Croatia. |
| Databáze: | OpenAIRE |
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