Bone mineral density changes in a free vascularised fibular graft in the distal femoral bone after osteosarcoma in a 10-year-old boy:a 7-year follow-up
| Autor: | Andrea René Jørgensen, Birgitte Jul Kiil, Maiken Stilling, Peter Holmberg Jørgensen |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
musculoskeletal diseases medicine.medical_specialty medicine.medical_treatment Osteoporosis Bone Neoplasms Case Report 03 medical and health sciences Absorptiometry Photon 0302 clinical medicine Bone Density Chondroblastic Osteosarcoma 030225 pediatrics medicine Humans Femur Child Bone mineral Osteosarcoma 030222 orthopedics Chemotherapy business.industry Standard treatment Cancer General Medicine medicine.disease Surgery Orthopedic surgery business Follow-Up Studies |
| Zdroj: | Jørgensen, A R, Jørgensen, P H, Jul Kiil, B & Stilling, M 2021, ' Bone mineral density changes in a free vascularised fibular graft in the distal femoral bone after osteosarcoma in a 10-year-old boy : a 7-year follow-up ', BMJ Case Reports, vol. 14, no. 3, e236097 . https://doi.org/10.1136/bcr-2020-236097 BMJ Case Rep |
| Popis: | A 10-year-old boy presented with continuous reports of pain located to the left knee. Imaging revealed a sclerotic process in the left distal femur, and biopsies were consistent with chondroblastic osteosarcoma. As part of standard treatment the patient underwent neoadjuvant chemotherapy followed by limb sparring surgery and adjuvant chemotherapy. The entire tumour was excised and femoral bone reconstruction was performed with a double barrel free vascularised fibular graft. Bone mineral density (BMD) can be decreased in childhood survivors of cancer. The patient was followed for 7 years with dual-energy X-ray absorptiometry scans in order to assess BMD and graft adaption. Despite two accidental fractures to the graft region local and global BMD underwent an overall increase. Approximately 7 years after tumour resection the patient had a global Z-score of 0.2, which is considered within normal range. |
| Databáze: | OpenAIRE |
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