Characteristics of patients diagnosed with AIDS shortly after first detection of HIV antibodies in Lyon University hospitals from 1985 to 2001*

Autor: Christian Trepo, Dominique Peyramond, J. Fabry, Laurent Cotte, Jean-Louis Touraine, Jean-Michel Livrozet, E Marceillac, Christian Chidiac, Philippe Vanhems, D. Baratin, R. Allard
Rok vydání: 2004
Předmět:
Zdroj: HIV Medicine. 5:273-277
ISSN: 1468-1293
1464-2662
DOI: 10.1111/j.1468-1293.2004.00220.x
Popis: Department of Public Health,McGill University, Montreal, Quebec, CanadaSummaryA diagnosis of AIDS shortly after the detection of HIV antibodies suggests a long-lasting course ofthe disease without care. The factors associated with a short delay between the initial HIV-1-positivetest and the first AIDS-defining event were identified in 1901 patients from 1985 to 2001 in LyonUniversity hospitals. A total of 576 individuals (30.3%) had an interval of 3 months between thedetection of HIV infection and AIDS. The factors independently associated with a delay of 3months were: age from 30 to 44 years [odds ratio (OR) 2.5; 95% confidence interval (CI) 1.9–3.2]; agefrom 45 to 59 years (OR 5.6; 95% CI 3.9–7.8); age 60 years (OR 4.5; 95% CI 2.5–8.1), compared tothoseo30 years old; heterosexuality (OR 2.4; 95% CI 1.6–3.4); injection drug use (OR 2.1; 95% CI1.5–2.7); and other exposures (OR 2.4; 95% CI 1.6–3.4), compared to homosexual exposure; twoopportunistic infections at AIDS (OR 1.8; 95% CI 1.4–2.4) compared to one; and Pneumocystiscarinii pneumonia as initial AIDS event (OR 2.6; 95% CI 1.8–3.7), compared to Kaposi’s sarcoma.These results provide opportunities to refocus local public health interventions to reduce delayedaccess to care.Received: 20 August 2003, accepted 19 January 2004
Databáze: OpenAIRE