Treatment of experimentally induced bovine respiratory disease in young calves with a single administration of a combination of florfenicol and meloxicam
| Autor: | Agathe Caruso-Vares, Jean-François Collin, Damien Achard, Cliff Ramage, David Reddick, Joanne McKelvie |
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| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine Florfenicol Flunixin 040301 veterinary sciences medicine.drug_class medicine.medical_treatment Respiratory Tract Diseases 030106 microbiology Antibiotics Cattle Diseases Bovine respiratory disease Meloxicam 0403 veterinary science Andrology Random Allocation 03 medical and health sciences chemistry.chemical_compound Pharmacokinetics medicine Animals Potency Saline Thiamphenicol General Veterinary business.industry fungi 04 agricultural and veterinary sciences General Medicine medicine.disease Anti-Bacterial Agents Drug Combinations Treatment Outcome chemistry Cattle Female business medicine.drug |
| Zdroj: | Veterinary Record. 183:535-535 |
| ISSN: | 0042-4900 |
| Popis: | This study was designed to evaluate the efficacy of a new florfenicol/meloxicam combination (FMC) in calves with bovine respiratory disease. A total of 90 young calves were challenged via intratracheal deposition of 108 colony-forming units of Mannheimia haemolytica. Data for 84 calves demonstrating a rectal temperature (RT) above 39.5°C and a combined total clinical score (TCS) greater than or equal to 3 were included. Calves were then randomly allocated to one of the three study groups (FMC; florfenicol/flunixin combination (FFC); or saline) and promptly treated. RT and TCS of calves treated with an FMC or FFC were consistently lower than RT and TCS of calves belonging to the control group (P |
| Databáze: | OpenAIRE |
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