Analysis of multiple factors involved in acute progressive cerebral infarction and extra- and intracranial arterial lesions
| Autor: | Binru Su, Yajie Liu, Weiheng Lu, Chenghong Luo, Yuefu Chen |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Cancer Research
Pathology medicine.medical_specialty medicine.diagnostic_test Cerebral infarction business.industry carotid atherosclerosis stroke in progression General Medicine Articles cerebral artery stenosis medicine.disease progressive cerebral infarction Cerebral artery stenosis chemistry.chemical_compound Stenosis Blood pressure Immunology and Microbiology (miscellaneous) chemistry Low-density lipoprotein Diabetes mellitus Conventional PCI medicine business Cerebral angiography |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-0981 |
| Popis: | In order to identify the potential factors involved in the development of acute progressive cerebral infarction (PCI), the association between potential risk factors and extra- and intracranial arterial lesions was investigated. A total of 608 patients underwent cerebral angiography to analyze the morphological characteristics between the PCI and NPCI groups. In addition, data from numerous cases of extra- and intracranial arterial lesions were collected and compared with the control groups, and the associations between the severity of arterial lesions and the potential influential factors were analyzed. In the blood vessels responsible for cerebral infarction, various degrees of atherosclerotic plaques and stenosis were observed. Age, high-density lipoprotein (HDL) levels, glycosylated hemoglobin and blood pressure affected the degrees of hardening, plaques and stenosis. Analysis of cerebral artery stenosis revealed that age, diabetes mellitus and plasma fibrinogen were risk factors for cerebral artery stenosis, while the HDL/low density lipoprotein ratio was a protective factor. Therefore, the results of the present study indicate that the lesions of blood vessels are a major pathological change in PCI and multiple factors are involved in the pathogenesis. |
| Databáze: | OpenAIRE |
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